Purgo Pil may be available in the countries listed below.
Ingredient matches for Purgo Pil
Bisacodyl
Bisacodyl is reported as an ingredient of Purgo Pil in the following countries:
- Belgium
- Luxembourg
International Drug Name Search
Thursday, 29 September 2016
Metolazone
In the US, Metolazone (metolazone systemic) is a member of the drug class thiazide diuretics and is used to treat Edema and High Blood Pressure.
US matches:
- Metolazone
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
C03BA08
CAS registry number (Chemical Abstracts Service)
0017560-51-9
Chemical Formula
C16-H16-Cl-N3-O3-S
Molecular Weight
365
Therapeutic Category
Diuretic agent
Chemical Name
6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-
Foreign Names
- Metolazonum (Latin)
- Metolazon (German)
- Métolazone (French)
- Metolazona (Spanish)
Generic Names
- Metolazone (OS: JAN, USAN, DCIT, BAN)
- Métolazone (OS: DCF)
- SR 720-22 (IS)
- Metolazone (PH: Ph. Eur. 6, USP 32, BP 2010)
- Metolazonum (PH: Ph. Eur. 6)
Brand Names
- Diulo
Pfizer, Portugal - Metenix
IFET, Greece; Sanofi-Aventis, United Kingdom - Metolaz
Centaur, India - Metolazon Galepharm
Galepharm, Switzerland - Metolazone
Mylan, United States; Sandoz, United States - Metoz
Centaur, India - Mykrox
Orient Europharma, Taiwan - Pavedal
Pharma Investi, Chile - Zaroxolyn
Celltech, Hong Kong; Celltech, Israel; Orient Europharma, Taiwan; sanofi-aventis, Canada; Teofarma, Italy; UCB, United States
International Drug Name Search
Glossary
| BAN | British Approved Name |
| DCF | Dénomination Commune Française |
| DCIT | Denominazione Comune Italiana |
| IS | Inofficial Synonym |
| JAN | Japanese Accepted Name |
| OS | Official Synonym |
| PH | Pharmacopoeia Name |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
Click for further information on drug naming conventions and International Nonproprietary Names.
Wednesday, 28 September 2016
Zorclone
Zorclone may be available in the countries listed below.
Ingredient matches for Zorclone
Eszopiclone
Zopiclone is reported as an ingredient of Zorclone in the following countries:
- Ireland
International Drug Name Search
Mefoxin
Generic Name: cefoxitin (sef OX i tin)
Brand Names: Mefoxin
What is cefoxitin injection?
Cefoxitin is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works by fighting bacteria in your body.
Cefoxitin is used to treat many kinds of bacterial infections, including severe or life-threatening forms.
Cefoxitin may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Mefoxin (cefoxitin)?
Do not use this medication if you are allergic to cefoxitin, or to similar antibiotics, such as Ceftin, Cefzil, Keflex, Omnicef, and others.
Before using this medication, tell your doctor if you are allergic to any drugs (especially penicillin). Also tell your doctor if you have liver or kidney disease, diabetes, heart failure, cancer, a stomach or intestinal disorder, or if you are malnourished.
Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefoxitin will not treat a viral infection such as the common cold or flu.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
This medication can cause you to have unusual results with certain lab tests, including tests to check for glucose (sugar) in the urine. Tell any doctor who treats you that you are using cefoxitin.
What should I discuss with my health care provider before using cefoxitin injection?
Do not use this medication if you are allergic to cefoxitin, or to other cephalosporin antibiotics, such as:
cefaclor (Raniclor);
cefadroxil (Duricef);
cefazolin (Ancef);
cefdinir (Omnicef);
cefditoren (Spectracef);
cefpodoxime (Vantin);
cefprozil (Cefzil);
ceftibuten (Cedax);
cefuroxime (Ceftin);
cephalexin (Keflex);
cephradine (Velosef); and others.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely take cefoxitin:
kidney disease;
liver disease;
a stomach or intestinal disorder such as colitis;
diabetes;
congestive heart failure;
cancer;
if you are malnourished; or
if you have had a very recent surgery or medical emergency.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Cefoxitin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How is cefoxitin given?
Cefoxitin is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to inject your medicine at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and other items used in giving the medicine.
Use the medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.
Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Cefoxitin will not treat a viral infection such as the common cold or flu.
This medication can cause you to have unusual results with certain lab tests, including tests to check for glucose (sugar) in the urine. Tell any doctor who treats you that you are using cefoxitin.
To be sure this medication is helping your condition, your blood may need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
If you keep this medicine at home, store it in a deep freezer at a temperature of 4 degrees below 0.
To use the medicine, thaw it in a refrigerator or at room temperature. Do not warm in a microwave or boiling water. Keep thawed medicine in the refrigerator and use it within 28 days after thawing it. Do not refreeze.
Do not use the medication if it looks cloudy or has any particles in it. Call your doctor for a new prescription.
What happens if I miss a dose?
Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a cefoxitin overdose may include seizure (convulsions).
What should I avoid while using Mefoxin (cefoxitin)?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Mefoxin (cefoxitin) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
diarrhea that is watery or bloody;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
swelling, pain, or irritation where the injection was given;
skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
feeling light-headed, fainting;
easy bruising or bleeding, unusual weakness;
fever, chills, body aches, flu symptoms;
urinating less than usual or not at all;
seizure (black-out or convulsions); or
jaundice (yellowing of the eyes or skin).
Less serious side effects are more likely to occur, such as:
nausea, vomiting, stomach pain;
mild skin rash; or
vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Mefoxin (cefoxitin)?
Before using cefoxitin, tell your doctor if you are using any of the following drugs:
an antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), netilmicin (Netromycin), streptomycin, or tobramycin (Nebcin, Tobi).
This list is not complete and there may be other drugs that can interact with cefoxitin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
More Mefoxin resources
- Mefoxin Side Effects (in more detail)
- Mefoxin Use in Pregnancy & Breastfeeding
- Mefoxin Drug Interactions
- Mefoxin Support Group
- 0 Reviews for Mefoxin - Add your own review/rating
- Mefoxin Prescribing Information (FDA)
- Mefoxin MedFacts Consumer Leaflet (Wolters Kluwer)
- Mefoxin Monograph (AHFS DI)
- Mefoxin Advanced Consumer (Micromedex) - Includes Dosage Information
- Cefoxitin Prescribing Information (FDA)
Compare Mefoxin with other medications
- Aspiration Pneumonia
- Bone infection
- Cesarean Section
- Cholecystitis
- Deep Neck Infection
- Endometritis
- Gonococcal Infection, Uncomplicated
- Intraabdominal Infection
- Joint Infection
- Kidney Infections
- Pelvic Inflammatory Disease
- Peritonitis
- Pneumonia
- Septicemia
- Skin and Structure Infection
- Skin Infection
- Surgical Prophylaxis
- Urinary Tract Infection
Where can I get more information?
- Your doctor or pharmacist has information about cefoxitin written for health professionals that you may read.
See also: Mefoxin side effects (in more detail)
Tuesday, 27 September 2016
Medent-PE
Generic Name: guaifenesin and phenylephrine (gwye FEN e sin and FEN il EFF rin)
Brand Names: Aldex G, Aquatab D, Crantex, D-Phen 1000, D-Tab, Deconex, Deconsal II, Deconsal Pediatric, Despec, Donatussin Drops, Duomax, Duraphen 1000, Duraphen II, Duratuss, Dynex LA, ExeTuss, Extendryl G, Fenesin PE IR, Genexa LA, Gentex LA, Gilphex TR, Guaiphen-D 1200, Guaiphen-D 600, Guaiphen-PD, Guiadex PD, Guiatex PE, J-Max, Liquibid D-R, Liquibid-D, Liquibid-PD, Lusonex, Maxiphen, Medent-PE, MontePhen, Mucinex Children's Cold, Mucus Relief Sinus, Mydex, Nariz, Nasex, Nescon-PD, Nexphen PD, Norel EX, PE-Guai, Pendex, Prolex D, Refenesen PE, Reluri, Rescon-GG, Respa-PE, Robitussin Head & Chest Congestion, Simuc, Simuc-GP, Sina-12X, Sinupan, SINUvent PE, Sitrex PD, Sudafed PE Non-Drying Sinus, Sudex, Triaminic Chest & Nasal Congestion, Visonex, Wellbid-D, Xedec, Xedec II, Xpect-PE, Zotex GPX
What is Medent-PE (guaifenesin and phenylephrine)?
There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of guaifenesin and phenylephrine is used to treat stuffy nose and sinus congestion, and to reduce chest congestion caused by the common cold or flu.
Guaifenesin and phenylephrine may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Medent-PE (guaifenesin and phenylephrine)?
There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.
Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. Guaifenesin and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains guaifenesin or phenylephrine.
What should I discuss with my healthcare provider before taking Medent-PE (guaifenesin and phenylephrine)?
You should not use this medication if you are allergic to guaifenesin or phenylephrine, or to other decongestants, diet pills, stimulants, or ADHD medications. Do not use guaifenesin and phenylephrine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use guaifenesin and phenylephrine before the MAO inhibitor has cleared from your body.
Ask a doctor or pharmacist if it is safe for you to take this medication if you have:
heart disease or high blood pressure;
diabetes;
circulation problems;
glaucoma;
overactive thyroid; or
enlarged prostate or problems with urination.
It is not known if this medication may be harmful to an unborn baby. Do not use this medication without your doctor's advice if you are pregnant. This medication passes into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.
How should I take Medent-PE (guaifenesin and phenylephrine)?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.
Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.
Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Take guaifenesin and phenylephrine with food if it upsets your stomach. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash. Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Since cough or cold medicine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, vomiting, numbness or tingly feeling, dizziness, and feeling restless or nervous.
What should I avoid while taking Medent-PE (guaifenesin and phenylephrine)?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of guaifenesin and phenylephrine. Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. Guaifenesin and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains guaifenesin or phenylephrine.
Avoid taking this medication with diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.
Medent-PE (guaifenesin and phenylephrine) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:
fast, pounding, or uneven heartbeat;
severe dizziness, anxiety, restless feeling, or nervousness;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure); or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
vomiting, upset stomach;
warmth, tingling, or redness under your skin;
feeling excited or restless (especially in children);
sleep problems (insomnia);
skin rash or itching;
headache; or
dizziness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Medent-PE (guaifenesin and phenylephrine)?
Ask a doctor or pharmacist if it is safe for you to take guaifenesin and phenylephrine if you are also using any of the following drugs:
medicines to treat high blood pressure;
a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or
an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan, Silenor), desipramine (Norpramin), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others.
This list is not complete and other drugs may interact with guaifenesin and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More Medent-PE resources
- Medent-PE Side Effects (in more detail)
- Medent-PE Use in Pregnancy & Breastfeeding
- Medent-PE Drug Interactions
- Medent-PE Support Group
- 0 Reviews for Medent-PE - Add your own review/rating
- Crantex Prescribing Information (FDA)
- Despec Drops MedFacts Consumer Leaflet (Wolters Kluwer)
- Entex LA Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)
- Gentex LA Sustained-Release Tablets (12 Hour) MedFacts Consumer Leaflet (Wolters Kluwer)
- Guiatex PE Prescribing Information (FDA)
- Lusonex Controlled-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)
- Rescon-GG Liquid MedFacts Consumer Leaflet (Wolters Kluwer)
- Sina-12X Suspension MedFacts Consumer Leaflet (Wolters Kluwer)
Compare Medent-PE with other medications
- Cough and Nasal Congestion
- Sinus Symptoms
Where can I get more information?
- Your pharmacist can provide more information about guaifenesin and phenylephrine.
See also: Medent-PE side effects (in more detail)
Adcetris
Pronunciation: bren-TUX-i-mab
Generic Name: Brentuximab
Brand Name: Adcetris
A certain severe condition called progressive multifocal leukoencephalopathy (PML) has been reported with use of Adcetris. PML is often fatal. Discuss any questions or concerns with your doctor. Tell your doctor right away if you notice new or worsening symptoms, such as confusion; memory problems; difficulty talking or walking; changes in mood or behavior; or changes in thinking, eyesight, balance, or strength.
Adcetris is used for:
Treating certain types of lymphoma. It may also be used for other conditions as determined by your doctor.
Adcetris is a monoclonal antibody. It works by killing cancer cells.
Do NOT use Adcetris if:
- you are allergic to any ingredient in Adcetris
- you are taking bleomycin
Contact your doctor or health care provider right away if any of these apply to you.
Before using Adcetris:
Some medical conditions may interact with Adcetris. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of nerve problems (eg, nerve pain)
- if you have a history of an infusion-related reaction to Adcetris
Some MEDICINES MAY INTERACT with Adcetris. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Bleomycin because the risk of lung problems may be increased
- Certain azole antifungals (eg, itraconazole, ketoconazole, voriconazole), clarithromycin, nefazodone, protease inhibitors (eg, boceprevir, ritonavir), or telithromycin because they may increase the risk of Adcetris's side effects
- Carbamazepine, fosphenytoin, phenobarbital, phenytoin, primidone, rifamycins (eg, rifampin), or St. John's wort because they may decrease Adcetris's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Adcetris may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Adcetris:
Use Adcetris as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Adcetris is usually given as an injection at your doctor's office, hospital, or clinic.
- Do not shake Adcetris.
- Do not use Adcetris if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Adcetris, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Adcetris.
Important safety information:
- Adcetris may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Adcetris with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT use more than the recommended dose, stop using Adcetris, or use for longer than prescribed without checking with your doctor.
- Infusion-related reactions have occurred with the use of Adcetris. Your health care provider will monitor you for these reactions while you receive Adcetris. If you have experienced an infusion-related reaction before, you should receive certain other medicines (acetaminophen, an antihistamine, a corticosteroid) before you receive your dose of Adcetris. Contact your doctor right away if you experience breathing problems (eg, shortness of breath), chills, cough, fever, itching, nausea, or rash while you receive Adcetris or within 24 hours of the infusion. Discuss any questions or concerns with your doctor.
- Adcetris may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
- Adcetris may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- A serious and possibly fatal condition called tumor lysis syndrome (TLS) has been reported in certain patients taking Adcetris. Contact your doctor right away if you develop symptoms, such as fast or irregular heartbeat; fainting; decreased urination; muscle weakness or cramps; nausea, vomiting, diarrhea, or loss of appetite; or sluggishness. Discuss any questions or concerns with your doctor.
- Tell your doctor or dentist that you take Adcetris before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including complete blood cell counts, may be performed while you use Adcetris. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Adcetris should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Adcetris may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Adcetris while you are pregnant. It is not known if Adcetris is found in breast milk. Do not breast-feed while taking Adcetris.
Possible side effects of Adcetris:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Back pain; constipation; cough; diarrhea; dizziness; dry skin; hair loss; headache; joint pain; loss of appetite; mild muscle pain or spasms; mild sore throat or mouth pain; mild weight loss; night sweats; nausea; stomach pain; tiredness; trouble sleeping; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; changes in mood or behavior; changes in thinking, eyesight, balance, or strength; chest pain; confusion; coughing up blood; dark, tarry, or bloody stools; difficulty talking or walking; irregular heartbeat; memory problems; new or worsening nerve problems (eg, burning, numbness, or tingling; decreased or increased sense of touch or sensation; muscle weakness); red, swollen, blistered, or peeling skin; severe or persistent tiredness or weakness; shortness of breath; swelling of the hands, ankles, or feet; symptoms of infection (eg, fever; chills; persistent sore throat or cough; increased, difficult, or painful urination); unusual bruising or bleeding.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Adcetris side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include symptoms of infection (eg, fever, chills, persistent sore throat).
Proper storage of Adcetris:
Adcetris is usually handled and stored by a health care provider. If you are using Adcetris at home, store Adcetris as directed by your pharmacist or health care provider. Keep Adcetris out of the reach of children and away from pets.
General information:
- If you have any questions about Adcetris, please talk with your doctor, pharmacist, or other health care provider.
- Adcetris is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
Issue Date: February 1, 2012
Database Edition 12.1.1.002
Copyright © 2012 Wolters Kluwer Health, Inc.
More Adcetris resources
- Adcetris Side Effects (in more detail)
- Adcetris Use in Pregnancy & Breastfeeding
- Adcetris Drug Interactions
- Adcetris Support Group
- 0 Reviews for Adcetris - Add your own review/rating
- Adcetris Prescribing Information (FDA)
- Adcetris Advanced Consumer (Micromedex) - Includes Dosage Information
- Adcetris Consumer Overview
- Brentuximab Vedotin Professional Patient Advice (Wolters Kluwer)
Compare Adcetris with other medications
- Hodgkin's Lymphoma
- Lymphoma
Monday, 26 September 2016
Doxazosina Ratiopharm
Doxazosina Ratiopharm may be available in the countries listed below.
Ingredient matches for Doxazosina Ratiopharm
Doxazosin
Doxazosin mesilate (a derivative of Doxazosin) is reported as an ingredient of Doxazosina Ratiopharm in the following countries:
- Spain
International Drug Name Search
varenicline
Generic Name: varenicline (ver EN e kleen)
Brand names: Chantix, Chantix Starter Pack, Chantix Continuing Month
What is varenicline?
Varenicline is a smoking cessation medicine. It is used together with behavior modification and counseling support to help you stop smoking.
Varenicline may also be used for purposes not listed in this medication guide.
What is the most important information I should know about varenicline?
Before using varenicline, tell your doctor if you have heart disease, circulation problems, kidney disease, or a history of depression or mental illness. You may choose from 2 ways to use varenicline. Ask your doctor which of the following methods is best for you: To improve your chances for successful smoking cessation, be sure to quit smoking on your planned quit date.
After you stop smoking, the doses of any medications you are using may need to be adjusted. Tell your doctor about all other medicines you use, especially insulin, blood thinners, or asthma medication.
Stop using this medication and call your doctor at once if you have: any mood or behavior changes, confusion, anxiety, panic attacks, hallucinations, extreme fear, or if you feel impulsive, agitated, aggressive, restless, hostile, depressed, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. Varenicline may impair your thinking or reactions. You may also have mood or behavior changes when you quit smoking. Until you know how varenicline and the smoking cessation process is going to affect you, be careful if you drive or do anything that requires you to be cautious and alert.
What should I discuss with my health care provider before taking varenicline?
To make sure you can safely take varenicline, tell your doctor if you have any of these other conditions:
heart disease, circulation problems;
kidney disease (or if you are on dialysis); or
a history of depression or mental illness.
FDA pregnancy category C. It is not known whether varenicline will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether varenicline passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone under 18 years old
How should I take varenicline?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
You may choose from 2 ways to use varenicline. Ask your doctor which of the following methods is best for you:
Set a date to quit smoking and start taking varenicline one week before that date. This will allow the drug to build up in your body.
You may also start taking varenicline before you set a planned quit date. Once you start taking the medicine, choose a quit date that is between 8 and 35 days after you start treatment.
To improve your chances for successful smoking cessation, be sure to quit smoking on your planned quit date. Take varenicline after eating. Take the medicine with a full glass of water.
When you first start taking varenicline, you will take a low dose and then gradually increase your dose over the first several days of treatment. Follow your doctor's dosing instructions very carefully.
In most cases, varenicline treatment lasts for 12 weeks. Your doctor may recommend a second 12-week course of varenicline to improve the chance that you will quit smoking long-term.
Use varenicline regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. You should remain under the care of a doctor while taking varenicline.
Store at room temperature away from moisture and heat.
See also: Varenicline dosage (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking varenicline?
This medication may impair your thinking or reactions. You may also have mood or behavior changes when you quit smoking. Until you know how varenicline and the smoking cessation process are going to affect you, be careful if you drive or do anything that requires you to be cautious and alert.
Do not use other medications to quit smoking while you are taking varenicline, unless your doctor tells you to.
Varenicline side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any mood or behavior changes, confusion, anxiety, panic attacks, hallucinations, extreme fear, or if you feel impulsive, agitated, aggressive, restless, hostile, depressed, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Your family or other caregivers should also be alert to changes in your mood or behavior.
Call your doctor at once if you have any of these other serious side effects:
chest pain or pressure, tight feeling in your neck or jaw, pain spreading to your arm or shoulder, vomiting, sweating, general ill feeling;
feeling light-headed or short of breath;
sudden numbness or weakness, especially on one side of the body;
sudden severe headache, confusion, problems with vision, speech, or balance;
easy bruising, unusual bleeding, blood in your urine or stools, coughing up blood or vomit that looks like coffee grounds;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
the first sign of any blistering type of skin rash, no matter how mild.
Less serious side effects may include:
nausea (may persist for several months);
stomach pain, indigestion, constipation, gas;
weakness, tired feeling;
dry mouth, unpleasant taste in your mouth;
headache; or
sleep problems (insomnia) or unusual dreams.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Varenicline Dosing Information
Usual Adult Dose for Smoking Cessation:
Days 1 to 3: 0.5 mg orally once a day
Days 4 to 7: 0.5 mg orally twice a day
Days 8 to end of treatment: 1 mg orally twice a day
What other drugs will affect varenicline?
After you stop smoking, the doses of any medications you are using may need to be adjusted. Tell your doctor about all other medicines you use, especially:
insulin;
a blood thinner such as warfarin (Coumadin, Jantoven); or
asthma medication such as theophylline (Respbid, Theobid, Theoclear, Theo-Dur, Uniphyl).
This list is not complete and other drugs may interact with varenicline. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More varenicline resources
- Varenicline Side Effects (in more detail)
- Varenicline Dosage
- Varenicline Use in Pregnancy & Breastfeeding
- Varenicline Drug Interactions
- Varenicline Support Group
- 384 Reviews for Varenicline - Add your own review/rating
- varenicline Advanced Consumer (Micromedex) - Includes Dosage Information
- Varenicline Professional Patient Advice (Wolters Kluwer)
- Varenicline MedFacts Consumer Leaflet (Wolters Kluwer)
- Chantix Prescribing Information (FDA)
- Chantix Monograph (AHFS DI)
- Chantix Consumer Overview
Compare varenicline with other medications
- Smoking Cessation
Where can I get more information?
- Your pharmacist can provide more information about varenicline.
See also: varenicline side effects (in more detail)
Vigamox
Vigamox is a brand name of moxifloxacin ophthalmic, approved by the FDA in the following formulation(s):
VIGAMOX (moxifloxacin hydrochloride - solution/drops; ophthalmic)
Manufacturer: ALCON PHARMS LTD
Approval date: April 15, 2003
Strength(s): EQ 0.5% BASE [RLD]
Has a generic version of Vigamox been approved?
No. There is currently no therapeutically equivalent version of Vigamox available.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Vigamox. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: About generic drugs.
Related Patents
Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.
7-(1-pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives
Patent 4,990,517
Issued: February 5, 1991
Inventor(s): Petersen; Uwe & Schenke; Thomas & Krebs; Andreas & Grohe; Klaus & Schriewer; Michael & Haller; Ingo & Metzger; Karl G. & Endermann; Rainer & Zeiler; Hans-Joachim
Assignee(s): Bayer Aktiengesellschaft
7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives, of the formula ##STR1## in which X.sup.1 is halogen, X.sup.2 is hydrogen, halogen, amino or other radical, R.sup.1 is alkyl, cycloalkyl, optionally substituted phenyl or other radical, R.sup.2 is hydrogen, alkyl or a dioxolylmethyl radical, R.sup.3 is ##STR2## A is N, CH, C-halogen, or the like, or forms a bridge with R.sup.1, and addition products thereof.Patent expiration dates:
- December 8, 2011✓✓✓
- June 8, 2012✓
- December 8, 2011
7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives
Patent 5,607,942
Issued: March 4, 1997
Inventor(s): Petersen; Uwe & Schenke; Thomas & Krebs; Andreas & Grohe; Klaus & Schriewer; Michael & Haller; Ingo & Metzger; Karl G. & Endermann; Rainer & Zeiler; Hans-Joachim
Assignee(s): Bayer Aktiengesellschaft
7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives, of the formula ##STR1## in which X.sup.1 is halogen, X.sup.2 is hydrogen, halogen, amino or other radical, R.sup.1 is alkyl, cycloalkyl, optionally substituted phenyl or other radical, R.sup.2 is hydrogen, alkyl or a dioxolylmethyl radical, R.sup.3 is ##STR2## and A is N, CH, C-halogen, or the like, or forms a bridge with R.sup.1, and addition products thereof.Patent expiration dates:
- March 4, 2014✓✓✓
- September 4, 2014✓
- March 4, 2014
Ophthalmic antibiotic compositions containing moxifloxacin
Patent 6,716,830
Issued: April 6, 2004
Inventor(s): Gerald; Cagle & Robert L.; Abshire & David W.; Stroman & John M.; Yanni
Assignee(s): Alcon, Inc.
Ophthalmic, otic and nasal compositions containing a new class of antibiotics (e.g., moxifloxacin) are disclosed. The compositions preferably also contain one or more anti-inflammatory agents. The compositions may be utilized to treat ophthalmic, otic and nasal conditions by topically applying the compositions to the affected tissues.Patent expiration dates:
- September 29, 2019✓
- March 29, 2020✓
- September 29, 2019
Method of treating ophthalmic infections with moxifloxacin compositions
Patent 7,671,070
Issued: March 2, 2010
Inventor(s): Cagle; Gerald & Abshire; Robert L. & Stroman; David W. & Yanni; John M.
Assignee(s): Alcon, Inc.
Ophthalmic, otic and nasal compositions containing a new class of antibiotics (e.g., moxifloxacin) are disclosed. The compositions preferably also contain one or more anti-inflammatory agents. The compositions may be utilized to treat ophthalmic, otic and nasal conditions by topically applying the compositions to the affected tissues.Patent expiration dates:
- September 29, 2019✓
- March 29, 2020✓
- September 29, 2019
See also...
- Vigamox Consumer Information (Drugs.com)
- Vigamox Drops Consumer Information (Wolters Kluwer)
- Vigamox Consumer Information (Cerner Multum)
- Vigamox Advanced Consumer Information (Micromedex)
- Vigamox eent AHFS DI Monographs (ASHP)
- Moxifloxacin Drops Consumer Information (Wolters Kluwer)
- Moxifloxacin ophthalmic Consumer Information (Cerner Multum)
- Moxifloxacin Ophthalmic Advanced Consumer Information (Micromedex)
- Moxifloxacin Hydrochloride eent AHFS DI Monographs (ASHP)
Medi-Paste
Generic Name: zinc oxide topical (ZINK OX ide)
Brand Names: ARC, Balmex, Boudreaux Butt Paste, Caldesene, Calmol-4 Suppository, Critic-Aid Skin Paste, Delazinc, Dermagran BC, Desitin, Desitin Maximum Strength Original, Desitin Rapid Relief Creamy, Diaper Rash Ointment, Diaper Relief, Dr. Smith's Diaper, Flanders Buttocks Ointment, Geri-Protect, Medi-Paste, PeriGuard, Pinxav, Rash Relief, RVPaque, Seniortopix Healix, Soothe & Cool Skin Paste, Sportz Block Dark, Sportz Block Light, Sportz Block Medium, Triple Paste, Tronolane Suppositories, Unna-Flex Elastic Unna Boot 3 inch, Unna-Flex Elastic Unna Boot 4 inch, Znlin
What is Medi-Paste (zinc oxide topical)?
Zinc oxide is a mineral.
Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.
Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements.
Zinc oxide topical may also be used for purposes not listed in this medication guide.
What is the most important information I should know about Medi-Paste (zinc oxide topical)?
You should not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.
Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.
Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.
Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment. Avoid getting this medication in your mouth or eyes. If this does happen, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.
Avoid using other medications on the areas you treat with zinc oxide unless you doctor tells you to.
What should I discuss with my health care provider before using Medi-Paste (zinc oxide topical)?
You should not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.
Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.
It is not known whether zinc oxide topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether zinc oxide topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without medical advice if you are breast-feeding a baby.
How should I use Medi-Paste (zinc oxide topical)?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Apply enough of this medication to cover the entire area to be treated. Zinc oxide often leaves a thin white residue that may not be entirely rubbed in.
To treat chapped skin, minor burn wounds, or other skin irritations, use the medication as often as needed. Apply a thin layer to the affected area and rub in gently.
To treat diaper rash, use this medication each time the diaper is changed. It is especially important to apply the medication at bedtime or whenever there will be a long period of time between diaper changes.
Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.
When using the powder form of this medicine, pour the powder slowly to avoid a large puff into the air. Do not allow a baby to handle a powder bottle during use. Always close the lid after using the powder.
Zinc oxide rectal suppositories come with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Wash your hands before and after inserting a rectal suppository.
Try to empty your bowel and bladder just before using the suppository. Cleanse and dry your rectal area thoroughly.
Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.
For best results, stay lying down after inserting the suppository and hold it in your rectum for a few minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in.
Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment. Store at room temperature away from moisture and heat. Keep the tube cap tightly closed when not in use. You may store zinc oxide rectal suppositories in a refrigerator to prevent melting.
What happens if I miss a dose?
Since zinc oxide is used on an as needed basis, you are not likely to miss a dose. Using extra zinc oxide to make up a missed dose will not make the medication more effective.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using Medi-Paste (zinc oxide topical)?
Avoid getting this medication in your mouth or eyes. If this does happen, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.
Medi-Paste (zinc oxide topical) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using zinc oxide rectal suppositories if you have rectal bleeding or continued pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Medi-Paste (zinc oxide topical)?
Avoid applying other skin medications on the same treatment area with zinc oxide, unless your doctor has told you to.
There may be other drugs that can interact with zinc oxide topical or rectal suppositories. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More Medi-Paste resources
- Medi-Paste Side Effects (in more detail)
- Medi-Paste Use in Pregnancy & Breastfeeding
- Medi-Paste Support Group
- 0 Reviews for Medi-Paste - Add your own review/rating
- Arcalyst Monograph (AHFS DI)
- Caldesene Topical Advanced Consumer (Micromedex) - Includes Dosage Information
- Desitin Cream MedFacts Consumer Leaflet (Wolters Kluwer)
Compare Medi-Paste with other medications
- Anal Itching
- Dermatologic Lesion
Where can I get more information?
- Your pharmacist can provide more information about zinc oxide topical.
See also: Medi-Paste side effects (in more detail)
Friday, 23 September 2016
Medebar Suspension
Dosage Form: suspension
LAFAYETTE
MEDEBAR™ PLUS
BARIUM SULFATE SUSPENSION
Rx only
Medebar Suspension Description
Medebar Plus is a fruity-cola flavored, low viscosity (rapid flow), ready-to-use suspension, for x-ray examinations of the gastrointestinal tract.
It contains 100% w/v (55% w/w) barium sulfate USP, dispersing agent, vegetable gums, simethicone, preservatives, flavoring, saccharin sodium and water. Barium sulfate has the empirical formula of BaSO4.
Medebar Suspension - Clinical Pharmacology
Barium sulfate is an insoluble material which, because of its density, provides a positive contrast during x-ray examination. Barium sulfate is an inert radiopaque material which is not absorbed or metabolized and is eliminated intact from the body in a manner similar to other non-absorbed inorganic materials. Excretion rate is a function of gastrointestinal transit time.
Indications and Usage for Medebar Suspension
Medebar Plus is indicated for use as a contrast medium in x-ray diagnosis of the gastrointestinal tract. The suspension may be administered without dilution for double contrast colon, single contrast esophagus, small bowel and enteroclysis examinations. Aqueous dilutions of Medebar Plus may be used for single contrast stomach and single contrast colon examinations.
Contraindications
Barium sulfate products are contraindicated in patients with known or suspected obstruction of the colon, known or suspected gastrointestinal tract perforation, suspected tracheoesophageal fistula, obstructing lesions of the small intestine, pyloric stenosis, inflammation or neoplastic lesions of the rectum, recent rectal biopsy, or known hypersensitivity to barium sulfate formulations.
Known hypersensitivity or allergy to latex is a contraindication for the use of balloon retention enema tips containing latex. The use of a retention cuff enema tip is not necessary or desirable in patients with normal sphincter tone. The presence of adequate sphincter tone can be judged by preliminary rectal digital examination.
The use of rectal balloon is contraindicated in patients having a history of pencil stools, recent rectal surgery or low rectal anastomosis, perianal inflammation, colitis, rectal stricture or other suspected lesions that could lead to further injury through distention by a rectal balloon or when proctitis or other rectal conditions such as inflammatory or neoplastic diseases are suspected.
Warnings
Serious adverse reactions, including death, have been reported with the administration of barium sulfate formulations and are usually associated with the technique of administration, the underlying pathological condition and/or patient hypersensitivities.
Oral administration of barium sulfate suspension by an infant sucking a bottle and administration of large quantities by catheter are reported to be likely to result in aspiration into the tracheobronchial tree.
Vomiting following oral administration of barium sulfate may lead to aspiration pneumonitis. Cardiopulmonary arrest leading to fatality has been reported in infants following aspiration. Aspiration of smaller amounts may cause inflammation.
Barium sulfate preparations used as radiopaque media contain a number of additives to provide diagnostic properties and patient palatability. Allergic responses following the use of barium sulfate suspensions have been reported. In patients with increased cranial pressure, barium sulfate suspension enemas present an additional risk of further increasing intracranial pressure.
Barium sulfate suspension intravasation can be a serious complication. Mortality has been reported as a result of vaginal or rectal intravasation and is believed to be due to massive pulmonary embolism occurring within minutes of the inciting event.
Skin irritation, redness, inflammation and hives have been reported in infants and small children following spillage of barium sulfate suspension on their skin. These responses are thought to be caused by the flavors and/or preservatives used in the product.
Barium sulfate suspension has been reported to cause obstruction of the small bowel (impaction) in pediatric patients with cystic fibrosis. It has also been reported to cause fluid overload from the absorption of water during studies in infants when Hirschsprung’s Disease is suspected.
Care must be taken during the insertion of an enema tip into the patient to prevent application of pressure to the vagus nerve which can lead to vasovagal reactions and syncopal episodes. Cardiac arrhythmia or other cardiovascular side effects can occur as a result of colon distension.
Precautions
General
Diagnostic procedures which involve the use of radiopaque contrast agents should be carried out under the direction of personnel with the requisite training and with a thorough knowledge of the particular procedure to be performed. A history of bronchial asthma, atopy, as evidenced by hay fever and eczema, a family history of allergy, or a previous reaction to a contrast agent warrant special attention. Caution should be exercised with the use of radiopaque media in severely debilitated patients and in those with marked hypertension or advanced cardiac disease.
Anaphylactic and allergic reactions have been reported during double contrast examinations in which glucagon has been used.
Ingestion of barium sulfate suspension is not recommended in patients with a history of food aspiration. If barium sulfate suspension is aspirated into the larynx, further administration of the suspension should be immediately discontinued.
Patient preparation for diagnostic gastrointestinal examinations frequently requires cathartics and a liquid diet. The various preparations can result in water loss for the patient. Patients should be rehydrated quickly following a barium sulfate suspension examination of the gastrointestinal tract. In patients with reduced colon motility, saline cathartics may be required after the barium sulfate suspension enema. Saline cathartics are recommended on a routine basis in patients with a history of constipation unless clinically contraindicated.
Where enema tips are used, care must be taken during insertion into the patient, since forceful or too deep insertion may cause tearing or perforation of the rectum. Insertion of an enema tip should be done only after digital examination by qualified medical personnel. When balloon retention tips are used, care should be taken to avoid over-inflation of the balloon, since overfilling or asymmetrical filling may cause displacement of the tip. Such a displacement can lead to rectal perforation or barium sulfate granulomas. Inflation of the balloon should be done under fluoroscopic control by qualified medical personnel. Do not unnecessarily move the enema tip once inserted.
A specially designed enema tip is required for a barium sulfate suspension examination of a colostomy patient.
Intubation of an enteroclysis catheter should be done by qualified medical personnel. Perforation of the duodenum has been reported.
Because of reported anaphylactoid reactions to latex, the use of non-latex gloves during the procedure should be considered.
Pregnancy
Safe use of barium sulfate during pregnancy has not been established. Barium sulfate should be used in pregnant women only if the possible benefits outweigh the potential risks. Elective radiography of the abdomen is considered to be contraindicated during pregnancy due to the risk to the fetus from radiation exposure. Radiation is known to cause harm to the unborn fetus exposed in utero.
Adverse Reactions
Adverse reactions accompanying the use of barium sulfate formulations are infrequent and usually mild, though severe reactions (approximately 1 in 500,000) and fatalities (approximately 1 in 2,000,000) have occurred. Procedural complications are rare, but may include aspiration pneumonitis, barium sulfate impaction, granuloma formation, intravasation, embolization and peritonitis following intestinal perforation, vasovagal and syncopal episodes, and fatalities. EKG changes have been shown to occur following or during barium sulfate suspension enemas. It is of the utmost importance to be completely prepared to treat any such occurrence.
Due to the increased likelihood of allergic reactions in atopic patients, a complete history of known and suspected allergies as well as allergic-like symptoms, such as rhinitis, bronchial asthma, eczema and urticaria, must be obtained prior to any medical procedure.
Aspiration of large amounts of barium sulfate suspension may cause pneumonitis or nodular granulomas of interstitial lung tissues and lymph nodes; asphyxiation and death have been reported.
Transient bacteremia, beginning almost immediately and lasting up to 15 minutes, may occur during rectal administration of barium sulfate suspension, and rarely septicemia has been reported.
A rare mild allergic reaction would most likely be generalized pruritis, erythema or urticaria (approximately 1 in 100,000 reactions). Such reactions will often respond to an antihistamine. More serious reactions (approximately 1 in 500,000) may result in laryngeal edema, bronchospasm or hypotension.
Severe reactions which may require emergency measures are often characterized by peripheral vasodilation, hypotension, reflex tachycardia, dyspnea, bronchospasm, agitation, confusion and cyanosis, progressing to unconsciousness. Treatment should be initiated immediately according to established standard of care.
Apprehensive patients may develop weakness, pallor, tinnitus, diaphoresis and bradycardia following the administration of any diagnostic agent. Such reactions are usually non-allergic in nature.
Allergic reactions to the enema examination accessories, in particular to retention catheters (tips) with latex cuffs, can occur. Such reactions could occur immediately and result in the previously mentioned acute allergic-like responses or might be delayed in appearance and result in a contact dermatitis. Known atopic patients, particularly those with a history of asthma or eczema, should be evaluated for alternative methods of administration in order to avoid these adverse reactions. These plastic / rubber accessories are disposable, single-use devices that must not be reused or left in the body cavity for an extended period of time.
Postmarketing Experiences
The following adverse experiences have been reported in patients receiving products containing barium sulfate. These adverse experiences are listed alphabetically: abdominal cramping, abdominal pain, diarrhea, fever, foreign body trauma relating to procedural complications, headache, laryngeal burning and irritation, leukocytosis, nausea, procedural site reactions, rash and vomiting.
Overdosage
In rare instances, immediate repeat oral examinations utilizing standard dosages may lead to severe stomach cramps and diarrhea. Cases reported implicate total dose in the range of 30 ounces (900 mL) of suspension. Instances of this type have resolved spontaneously and they are not considered to be life-threatening.
Medebar Suspension Dosage and Administration
Patient Preparation
Successful examination of the upper gastrointestinal tract requires that the stomach be empty and essentially free of fluid. This can usually be accomplished by instructing the patient to abstain from eating or drinking anything after the evening meal before the examination. The preparation for small bowel examinations, done separately or combined with an upper gastrointestinal series, is the same.
For examinations of the colon, the patient should be given a low solid diet for a minimum of 24 hours before the examination. Laxatives should also be used to clean the colon. In order to obtain thorough cleansing of the colon, a 2 liter water enema one hour before the examination may be necessary.
Suspension Preparation
The volume and concentration used will vary depending upon the method of patient preparation, the desired level of contrast density, individual variation in patient anatomy and radiographic equipment. The following dilutions are suggested for Medebar Plus:
| TEST | DILUTION FORMULA | % BARIUM SULFATE (w/v) |
| Double Contrast Colon | Medebar Plus undiluted | 100 |
| Single Contrast Esophagus | Medebar Plus undiluted | 100 |
| Small Bowel, Enteroclysis | Medebar Plus undiluted | 100 |
| Single Contrast Stomach | Medebar Plus undiluted or diluted 1:1 with water | 100 50 |
| Single Contrast Colon | From 7 to 3 parts water to 1 part Medebar Plus | 14-33 |
| Shake VIGOROUSLY prior to use. | ||
Double Contrast Colon Examination:
The examination should be performed by properly trained medical personnel only. Approximately 500 mL Medebar Plus is required to reach the splenic flexure, and it should be introduced by an enema administration system.
An enema administration system with 1/2” ID tubing, such as Medebar Plus Kit or Aircon is used for ease of administration. The usual method uses introduced air to move the column of barium sulfate suspension around the hepatic flexure and into the cecum. Patient positioning is critical during this process to ensure that air does not get ahead of the barium column. Such an eventuality may reduce the volume of suspension that reaches the cecum, and will adversely affect the quality of its coating. Conversely, should excessive quantities of suspension flood the cecum, double contrast views may be obscured by the barium pool.
Double Contrast Colon Examination with Medebar Plus Kit
The following procedure is suggested for double contrast examination of a well prepared, adult colon using Medebar Plus Kit (650 mL Medebar Plus). The actual procedure used will depend upon patient symptoms and conditions as well as physician preference and judgement.
Shake the Medebar Plus bottle well and attach the tubing unit.
With the patient in the left lateral position and the right knee flexed, insert the enema tip and inflate the retention cuff. Introduce a small amount of Medebar Plus into the rectal area. Check the rectal area by fluoroscopy for contraindications.
Place the table slightly Trendelenburg. With the fluoroscopy unit off, introduce the remainder of the Medebar Plus. Close the clamp on the large bore tubing. Introduce approximately five pumps of air into the patient using the blue multi-puff insufflator provided with each case.
Turn the patient LAO and introduce five pumps of air. Turn the patient prone, bring the table horizontal and introduce five pumps of air. Turn the patient RAO and introduce five pumps of air. Position the patient right lateral and introduce five pumps of air. If, at this point, the barium sulfate suspension has not coated the cecum, tilt the patient slightly head up. This should bring the barium sulfate suspension pool to the cecum.
Next turn the patient supine and tilt the table slightly Trendelenburg. Turn the patient LPO and bring the table to horizontal. Turn the patient left lateral and position the table with the patient slightly head up. This should cause the barium sulfate suspension pool to collect in the rectal area.
Place the Medebar Plus bottle on the floor and open the 1/2” tubing clamp to drain excess barium sulfate suspension from the rectum. The physician may prefer to have the patient either left lateral or prone for rectal drainage. When drainage is complete, close the tubing clamp. Spot films of the rectosigmoid may now be obtained.
Fluoroscopy is then used to evaluate colon distension. Introduce additional air to provide optimum distension as determined by the physician. Removal of the enema tip at this time is optional, according to the preference of the examiner. Rotate the patient slowly 360° taking spot films and overhead radiographs.
For single patient use only. Properly discard unused portion.
How is Medebar Suspension Supplied
Catalog No. 129794. NDC 68240-737-90. 900 mL bottle; twelve (12) bottles per case.
Medebar Plus Kit. Catalog No. 129722. NDC 68240-737-65. 650 mL bottles. Six (6) bottles with six (6) enema tip-tubing assemblies per case.
Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Protect from freezing.
Shake VIGOROUSLY prior to use.
Medebar™ All trademark rights reserved.
DIN: 02216388
Distributed in Canada by:
tyco Healthcare
Pointe-Claire, QC, Canada H9R 5H8
Establishment License # 100689-A
Made in Mexico
Manufactured by:
Mallinckrodt Inc.
St. Louis, MO 63042 USA
www.Mallinckrodt.com
MID 1295215
Rev 03/2009
DOUBLE CONTRAST
LOWER G.I.
- Fast-flowing
- 100% w/v
- Dilute for single contrast
tyco
Healthcare
Mallinckrodt
Package Label - Principal Display Panel - 900 mL Bottle
L A F A Y E T T E
MEDEBAR™ PLUS
BARIUM SULFATE SUSPENSION
DOUBLE CONTRAST / LOWER G.I. EXAMS
Rx only
NDC 68240-737-90
Catalog No. 129794
A fruity-cola flavored, low viscosity, ready-to-use 100% w/v (55% w/w) barium sulfate USP suspension for x-ray examinations of the gastrointestinal tract.
Contents: Barium sulfate USP, dispersing agent, vegetable gums, simethicone, preservatives, flavoring, saccharin sodium and water.
Contraindications: Do not use in patients with suspected gastrointestinal tract perforation or known hypersensitivity to barium sulfate formulations.
Dosage and Administration: See package insert for complete instructions.
Shake VIGOROUSLY prior to use.
For single patient use only. Properly discard unused portion.
Storage: Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Protect from freezing.
Net Contents: 900 mL
DIN: 02216388
Distributed in Canada by:
tyco Healthcare
Pointe-Claire, QC, Canada H9R 5H8
Establishment License # 100689-A
Made in Mexico
Manufactured by Mallinckrodt Inc.
St. Louis, MO 63042 USA
www.Mallinckrodt.com
MID 1600170
Rev 03/2009
O3™ ANTIMICROBIAL TECHNOLOGY
tyco/Healthcare
MALLINCKRODT
| MEDEBAR PLUS barium sulfate suspension | ||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||
| Marketing Information | |||
| Marketing Category | Application Number or Monograph Citation | Marketing Start Date | Marketing End Date |
| unapproved other | 12/01/2009 | ||
| Labeler - Mallinckrodt, Inc. (810407189) |
| Establishment | |||
| Name | Address | ID/FEI | Operations |
| Mallinckrodt Medical, S.A. de C.V. | 810407189 | analysis, manufacture | |
More Medebar Suspension resources
- Medebar Suspension Side Effects (in more detail)
- Medebar Suspension Use in Pregnancy & Breastfeeding
- Medebar Suspension Support Group
- 1 Review for Medebar - Add your own review/rating
Compare Medebar Suspension with other medications
- Computed Tomography
Thursday, 22 September 2016
Lisinopril Generic Health
Lisinopril Generic Health may be available in the countries listed below.
Ingredient matches for Lisinopril Generic Health
Lisinopril
Lisinopril dihydrate (a derivative of Lisinopril) is reported as an ingredient of Lisinopril Generic Health in the following countries:
- Australia
International Drug Name Search
Medihaler Ergotamine
Tear off “Instructions for Use” and dispense with container in carton.
Medihaler Ergotamine Description
Medihaler Ergotamine (ergotamine tartrate) is an oral aerosol device which contains a fine particle suspension of 9.0 mg ergotamine tartrate per ml in an insert, nontoxic aerosol vehicle. The inert ingredients are dichlorodifluoromethane, dichlorotetrafluoroethane, sorbitan trioleate and trichloromonofluoromethane. Each depression of the valve delivers a measured dose of 0.36 mg to the patient.
ACTION
Ergotamine exerts a constrictor action upon cranial vessels.
INDICATIONS
As therapy to abort vascular headache, e.g., migraine, migraine variants, or so-called “histaminic cephalalgia.”
Contraindications
Ergotamine tartrate should not be used in the presence of coronary artery disease, peripheral vascular disease, hypertension, impaired renal or hepatic function, infectious states or malnutrition.
Ergotamine tartrate is contraindicated in patients with a history of hypersensitivity reactions.
Pregnancy: Ergotamine tartrate is contraindicated in pregnancy.
Warnings
Patients who are being treated with Medihaler Ergotamine should be informed adequately of the symptoms of ergotism. Close medical supervision by the physician is recommended so that he may react appropriately should signs of ergotism develop. Six inhalations per day, if continued daily, entail the risk of vasospastic complications. Avoid prolonged administration or in excess of the recommended dosage because of the danger of ergotism and gangrene.
Pediatric Patients: Since there is no experience in children who have received this drug, safety and efficacy in children have not been established.
Nursing Mothers: Whether ergotamine tartrate is excreted in mothers' milk is not known. As a general rule, nursing should not be undertaken while a patient is on a drug (since many drugs are excreted in human milk).
Adverse Reactions
Ergotamine tartrate may cause nausea and vomiting. Patients with headaches may become nauseated and drug induced distress may be difficult to evaluate.
Ergotamine in large doses raises arterial pressure, produces coronary vasoconstriction and slows the heart both by direct action and its effect on the vagus. Under this condition, ergotamine also has oxytocic and spasmolytic properties. The above conditions are seen as a consequence of overdosage and may be manifested at the dosage recommended for control of headaches.
Vasoconstrictive complications, at times of a serious nature, may occur. These include pulselessness, weakness, muscle pains and paresthesias of the extremities and precordial distress and pain. Although these effects occur most commonly with long term therapy at relatively high doses, they have also been reported with short term or normal doses. Other adverse effects include transient tachycardia or bradycardia, nausea, vomiting, localized edema and itching.
Medihaler Ergotamine Dosage and Administration
Adults: A single oral inhalation at the first sign of a headache or prodrome. Repeat this procedure in 5 minutes if relief is not obtained. Space and additional inhalations at no less than 5-minute intervals. No more than 6 inhalations should be administered in any 24-hour period, and no more than 15 in a one week period.
Children: A recommended dose for children has not been determined.
DIRECTIONS FOR USE:
Before each use, remove dust cap and shake MEDIHALER ERGOTAMINE.
- Breathe out fully and place mouthpiece well into the mouth, aimed at the back of the throat.
- As you begin to breathe in deeply, press the vial firmly down into the adapter with the index finger. This releases one dose.
- Release pressure on the vial and remove unit from mouth. Hold the breath as long as possible, then breathe out slowly.
How is Medihaler Ergotamine Supplied
Metal vial (2.5 ml) and adapter. Each depression of the valve delivers 0.36 mg ergotamine tartrate.
(NDC 0089-0762-21)
CAUTION
Federal law prohibits dispensing without prescription.
CONTENTS UNDER PRESSURE
Do not puncture or incinerate container. Do not expose to heat or store at temperatures above 120°F. KEEP OUT OF THE REACH OF CHILDREN.
3M Riker
3M Health Care
Northridge, CA 91324
ERG-16
JUNE 1989
INSTRUCTIONS FOR USE OF
Medihaler Ergotamine®
(ergotamine tartrate)
FOR ORAL INHALATION THERAPY ONLY
SHAKE WELL before each use.
To get the medication deep into lungs, follow these five simple steps. (can be completed within 5 seconds):
- Remove dust cap and inspect mouthpiece for dirt and foreign objects.
- Empty the lungs as completely as possible by exhaling, and insert open end of plastic mouthpiece into mouth.
- After beginning to inhale deeply, press the top of the metal vial downward, as you would a push-button; this releases one measured dose of the medication. Complete taking the deep breath, which draws medication into your lungs.
- Remove mouthpiece and hold breath for as long as possible. This distributes the medication in the lungs
- Exhale slowly, keeping the lips nearly closed.
Start with one inhalation – then wait five minutes; if not relieved, use Medihaler Ergotamine again. Any additional inhalations should be spaced at intervals of no less than five minutes. Take no more than six inhalations in any 24-hour period, and no more than 15 in a one-week period. Medihaler Ergotamine was designed to deliver a full dose for most people in one or two inhalations. Do not use Medihaler Ergotamine indiscriminately; use only the number of inhalations actually required for relief.
The oral adapter (plastic mouthpiece) should be kept clean. Simply remove metal vial and wash oral adapter with soap and hot water and rinse thoroughly. Dry and replace the vial and the dust cap.
WARNING: CONTENTS UNDER PRESSURE.
Do not puncture or incinerate container. Do not expose to heat or store at temperatures above 120°F. Keep out of the reach of children.
Medihaler Ergotamine®
(ergotamine tartrate)
For speed of relief and convenience the Medihaler Ergotamine oral inhaler comes ready-to-use. It consists of two parts:
- A metal vial, containing the medication, with a single dose valve, which fits into
- The oral adapter (plastic mouthpiece) with dust cap. The vial can be used only with Medihaler Ergotamine oral adapter.
ADVANTAGES:
- Provides relief with seconds
- Assures a uniform, measured dose with each depression of the vial
- Economical; all the medication is utilized; no loss or waste
3M Riker
3M Health Care
Northridge, CA 91324
JUNE 1989
| MEDIHALER ERGOTAMINE ergotamine tartrate aerosol, metered | |||||||||||||||||||||
| |||||||||||||||||||||
| |||||||||||||||||||||
| |||||||||||||||||||||
| |||||||||||||||||||||
Revised: 07/20063M Riker
More Medihaler Ergotamine resources
- Medihaler Ergotamine Side Effects (in more detail)
- Medihaler Ergotamine Use in Pregnancy & Breastfeeding
- Medihaler Ergotamine Drug Interactions
- Medihaler Ergotamine Support Group
- 2 Reviews for Medihaler Ergotamine - Add your own review/rating
Compare Medihaler Ergotamine with other medications
- Migraine
Subscribe to:
Posts (Atom)